YMC-Pack PVA-Sil
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Polyvinyl alcohol functionalized silica.
YMC-Pack PVA-Sil is prepared from a 5µm, 120 Å silica support which is bonded with a monomolecular polymer coating of vinyl alcohol. The polymerized PVA completely covers both external and internal surfaces of the silica support, protecting it against aggressive, high pH buffers and solvents.
YMC-Pack PVA-Sil is an excellent alternative to silica gel or other polar bonded phases used in normal phase chromatography. In many situations, it exhibits better performance characteristics with a unique selectivity, and can often resolve compounds that behave poorly on bare silica. The alcohol functionality present on PVA-Sil is better suited for troublesome compounds, such as organic bases, than the acidic silanols present in unbonded silica. Since PVA-Sil is a bonded stationary phase, it can be washed with solvents of any polarity from hexane to water, without altering the surface activity. Therefore; selectivity, retention, and resolution are reproducible regardless of the column’s previous history.
Characteristics
- Bonded phase alternative to silica for normal-phase applications
- Vinyl alcohol polymerized silica support
- Consistent surface activity, unaffected by water
- Excellent for packed column supercritical fluid chromatography
Applications
Typical applications include: phospholipid classes
Specifications
| Stationary Phase | polyvinyl alcohol (USP L24) |
|---|---|
| Bonding | Monomeric |
| Particle Size | 5 µm |
| Pore Size | 120 Å |
| pH Range | 2 – 9.5 |
| Temperature Upper Limit | 50 °C |
| Temperature Recommended Range | 20 – 40 °C |
Available Formats
- Prepacked columns & guards
- Capillary (< 1 mm ID)
- Analytical (1.0 – 8.0 mm ID)
- Preparative (10 mm ID & above)
- Bulk resin
