YMC-SEC MAB
Size exclusion chromatography (SEC) column for mAb separations.
YMC-SEC MAB is a silica based size exclusion chromatography column specifically designed for antibody separations.
Optimized base material design and surface modification provide superior separation of antibody monomers and their aggregates/fragments with very low nonspecific adsorption. This is ideal for the quality control assessment of antibody drugs.
YMC-SEC MAB exhibits excellent resolution and peak shape over a wide molecular weight range of 10 kDa to 700 kDa.
Characteristics
- Excellent resolution and peak shapes
- Optimized for separating aggregates and fragments of mAbs
- Suitable for SEC analysis of antibody drug conjugates (ADCs) using organic-containing mobile phases
Applications
Typical applications include: antibodies, aggregates, fragments, large proteins
Specifications
| Specifications | |
|---|---|
| Stationary Phase | dihydroxypropyl (USP L20, L59) |
| Mode | SEC |
| Particle Size | 3 µm |
| Pore Size | 250 Å |
| pH Range | 5-7.5 |
| Temperature Limit | 40 °C |
LC Columns & Accessories
| Product | Phase / Type | Separation Mode(s) | Pore Sizes | Particle Sizes | pH Range | Available Formats | Link to Order |
|---|---|---|---|---|---|---|---|
| YMC-SEC MAB | Dihydroxypropyl | Size Exclusion (SEC) | 250 Å | 3 µm | 5 - 7.5 | Analytical (1 - 8 mm ID)Capillary (< 1 mm ID) |
