YMC-Pack PVA-Sil

YMC-Pack PVA-Sil is prepared from a 5µm, 120 Å silica support which is bonded with a monomolecular polymer coating of vinyl alcohol. The polymerized PVA completely covers both external and internal surfaces of the silica support, protecting it against aggressive, high pH buffers and solvents.

YMC-Pack PVA-Sil is an excellent alternative to silica gel or other polar bonded phases used in normal phase chromatography. In many situations, it exhibits better performance characteristics with a unique selectivity, and can often resolve compounds that behave poorly on bare silica. The alcohol functionality present on PVA-Sil is better suited for troublesome compounds, such as organic bases, than the acidic silanols present in unbonded silica. Since PVA-Sil is a bonded stationary phase, it can be washed with solvents of any polarity from hexane to water, without altering the surface activity. Therefore; selectivity, retention, and resolution are reproducible regardless of the column’s previous history.