YMC-Pack Ph
Unique selectivity due to π-π interaction.
Phenyl columns provide unique selectivity when compared to aliphatic straight chain reversed phase materials such as C18, C8, and C4. The π electrons of the phenyl group can interact with the aromatic ring(s) of an analyte to increase retention relative to non-aromatic species. Phenyl also has application as an alternative to C18 and C4 for the analysis of peptides and proteins on both small-pore (120Å) and wide-pore (300Å) silica supports. Retention is decreased on wide-pore phenyl phases relative to 120Å material. Generally, as pore size increases, surface area decreases, resulting in shorter retention times.
Characteristics
- Monomerically-bonded phenyl
- Fully endcapped
- Preferential retention of aromatic compounds
- Alternative to alkyl-bonded phases for the analysis of peptides and other biomolecules
Applications
Typical applications include: aromatic compounds, phenols, fullerenes, sweeteners
Analytical Specifications
| YMC-Pack Ph | |
|---|---|
| Stationary Phase | phenyl (USP L11) |
| Bonding | Monomeric |
| Endcapping | Yes |
| Mode | Reversed Phase |
| Particle Size* | 3, 5 µm |
| Pore Size* | 120 Å |
| Carbon Content | 9% |
| pH Range | 2 – 7.5 |
| Temperature Upper Limit | 50 °C |
| Temperature Recommended Range | 20 – 40 °C |
*not all combinations of particle & pore size are available
Preparative Specifications
| YMC-Pack Ph-HG | |
|---|---|
| Stationary Phase | phenyl (USP L11) |
| Bonding | Monomeric |
| Endcapping | Yes |
| Mode | Reversed Phase |
| Particle Size* | 10, 15, 20, 50 µm |
| Pore Size* | 120, 200, 300 Å |
| Carbon Content | 9% |
| pH Range | 2 – 7.5 |
*not all combinations of particle & pore size are available
YMC-Pack Ph with particle sizes of 10 µm and higher are available as part of the YMC*Gel High Grade (HG) series. These resins boast improved mechanical stability as well as narrower particle size and pore size distribution.
YMC-Pack Ph-HG can be purchased in prepacked analytical and preparative columns or in bulk resin format.
Available Formats
- Prepacked columns & guards
- Capillary (< 1 mm ID)
- Analytical (1.0 – 8.0 mm ID)
- Preparative (10 mm ID & above)
- Bulk resin
LC Columns & Accessories
| Product | Phase / Type | Separation Mode(s) | Pore Sizes | Particle Sizes | pH Range | Available Formats | Link to Order |
|---|---|---|---|---|---|---|---|
| YMC-Pack Ph | Phenyl | Reversed Phase | 120 Å300 Å | 3 µm5 µm10 µm15 µm20 µm | 2 - 7.5 | Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID) |
