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YMC-Pack

YMC’s classic column phases.

The YMC-Pack Series includes multiple phases and modes of separation. These products are used in countless methods around the world, a testament to our longstanding reproducibility.

The high-strength “HG” version of the resins allow direct scale-up with particle sizes of 10 µm and above.

YMC-Pack Phase Comparison

Below is an overview of all YMC-Pack phases. For more information about a specific product, including applications and purchase options, click the product name.

Reversed Phase – C18s

Product Name Particle Size (µm) Pore Size (Å) Carbon Content USP pH Range Typical Applications Characteristics
YMC-Pack ODS-A & ODS-A-HG 3, 5, 10, 15, 20, 50 120, 200, 300 17%, 12%, 7% L1 2-7.5 validated API methods classical general-purpose phase, different pore sizes
YMC-Pack ODS-AL 5 120 17% L1 2-7.5 tocopherols, fat-soluble vitamins, disinfectants classical phase for mixed mode separations
YMC-Pack ODS-AM 3, 5 120 17% L1 2-7.5 purines, phenols, alkaloids classical general-purpose phase for validated methods operation
YMC-Pack ODS-AQ & ODS-AQ-HG 3, 5, 10, 15, 20, 50 120, 200 14%, 10% L1 2-7.5 strong polar compounds classical polar phase

Reversed Phase – Others

Product Name Phase Particle Size (µm) Pore Size (Å) Carbon Content USP pH Range Typical Applications Characteristics
YMC-Pack TMS & TMS-HG C1 3, 5, 10, 15, 20, 50 120, 200, 300 4% L13 2-7.5 water-soluble vitamins classical phase, very low hydrophobicity
YMC-Pack C4 & C4-HG C4 3, 5, 10, 15, 20, 50 120, 200, 300 7%, 5%, 3% L26 2-7.5 biological separations, polar compounds classical phase, different pore sizes, low hydrophobicity
YMC-Pack C8 & C8-HG C8 3, 5, 10, 15, 20, 50 120, 200, 300 10%, 7%, 4% L7 2-7.5 proteins and peptides, estrogens classical general-purpose phase with different pore sizes, moderate hydrophobicity
YMC-Pack CN & CN-HG cyano 3, 5, 10, 15, 20, 50 120, 200, 300 7%, 3% L10 2-7.5 steroids, catechols can be used in normal and reversed phase, useful for SFC applications
YMC-Pack Ph & Ph-HG phenyl 3, 5, 10, 15, 20, 50 120, 200, 300 9% L11 2-7.5 aromatic compounds, phenols, fullerenes, sweeteners reversed phase column with π electrons

Normal Phase

Product Name Phase Particle Size (µm) Pore Size (Å) USP pH Range Typical Applications Characteristics
YMC-Pack Diol-NP & Diol-NP-HG dihydroxypropyl 5, 10, 15, 20, 50 60, 120, 200, 300 L20 2-7.5 pharmaceutical products, metabolites, phospholipid classes normal phase separation using non-polar solvents, useful for hydrophilic interaction chromatography (HILIC)
YMC-Pack NH2 & NH2-HG aminopropyl 5, 10, 15, 20, 50 120, 200, 300 L8 2-7.5 saccharides, nucleotides, water-soluble vitamins primary amino derivative, high coverage monomeric bonding chemistry, suitable for HILIC
YMC-Pack PA-G polyamine 5 120 4-7.5 acidic oligosaccharides higher durability than conventional silica-based amino columns
YMC-Pack Polyamine II polyamine 5 120 L111 2-7.5 sugars, vitamins, fat-soluble compounds higher durability than conventional silica-based amino columns
YMC-Pack SIL & SIL-HG silica 3, 5, 10, 15, 20, 50 60, 80, 120, 200, 300 L3 2-7.5 steroids, fat-soluble vitamins, small organic molecules, tocopherols high grade silica
YMC-Pack PVA-Sil polyvinyl alcohol 5 120 L24 2-9.5 phospholipid classes high stability & reproducibility

SEC

Product Name Phase Particle Size (µm) Pore Size (Å) USP pH Range Typical Applications Characteristics
YMC-Pack Diol & Diol-HG Dihydroxypropyl 2, 3, 5, 10, 15, 20, 50 60, 120, 200, 300 L20, L33, L59 5-7.5 proteins, oligosaccharides, peptides, antibodies versatile phase for gel filtration separations of a wide range of molecular weights

LC Columns & Accessories

ProductPhase / TypeSeparation Mode(s)Pore SizesParticle SizespH RangeAvailable FormatsLink to Order
YMC-Pack C4C4Reversed Phase120 Å200 Å300 Å3 µm5 µm10 µm15 µm20 µm50 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack C8C8Reversed Phase120 Å200 Å300 Å3 µm5 µm10 µm15 µm20 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack CNCyanoNormal PhaseReversed Phase120 Å300 Å3 µm5 µm10 µm15 µm20 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack DiolDihydroxypropylSize Exclusion (SEC)120 Å200 Å300 Å60 Å3 µm5 µm10 µm15 µm2 µm5 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)
YMC-Pack Diol-NPDihydroxypropylNormal Phase120 Å300 Å60 Å3 µm5 µm15 µm20 µm50 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack NH2NH2Normal Phase120 Å3 µm5 µm10 µm15 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack ODS-AC18Reversed Phase120 Å200 Å300 Å3 µm5 µm10 µm15 µm20 µm50 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack ODS-ALC18Reversed Phase120 Å3 µm5 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack ODS-AMC18Reversed Phase120 Å3 µm5 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack ODS-AQC18Reversed Phase120 Å200 Å3 µm5 µm10 µm15 µm20 µm50 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack PA-GPolyamineNormal Phase120 Å5 µm4 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)
YMC-Pack PhPhenylReversed Phase120 Å300 Å3 µm5 µm10 µm15 µm20 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack Polyamine IIPolyamineNormal Phase120 Å5 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack PVA-SilPolyvinyl AlcoholNormal Phase120 Å5 µm2 - 9.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack SILBare SilicaNormal Phase120 Å60 Å3 µm5 µm10 µm15 µm20 µm50 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)
YMC-Pack TMSC1Reversed Phase120 Å3 µm5 µm10 µm15 µm20 µm2 - 7.5Analytical (1 - 8 mm ID)Preparative (10 mm ID & above)Capillary (< 1 mm ID)

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