YMC-BioPro HIC
Columns specifically designed for drug-to-antibody conjugates (ADCs) and antibodies.
YMC-BioPro HIC HT / BF are hydrophobic interaction chromatography (HIC) columns that utilize a butyl (C4) stationary phase bonded to non-porous hydrophilic polymer particles.
BioPro HIC HT offers higher resolution than conventional HIC columns and is the first choice for ADCs or mAbs.
BioPro HIC BF columns show a stronger retention and can therefore be used for the separation of low hydrophobic proteins or for the analysis of oxidized mAbs.
YMC-BioPro HIC columns are available in 4.6 mm ID.
Specifications
| BioPro HIC HT | BioPro HIC BF | |
|---|---|---|
| Base Particle | hydrophilic polymer (polymethacrylate) | hydrophilic polymer (polymethacrylate) |
| Particle Size (µm) | 2.3 | 4 |
| Pore | non-porous | non-porous |
| Functional Group | butyl | butyl |
| pH Range | 2-12 | 2-12 |
| Pressure Limit | 40 MPa (5,800 psi) | 20 MPa (2,900 psi) |
| Temperature Range | 10 – 60° C | 10 – 60° C |
LC Columns & Accessories
| Product | Phase / Type | Separation Mode(s) | Pore Sizes | Particle Sizes | pH Range | Available Formats | Link to Order |
|---|---|---|---|---|---|---|---|
| YMC-BioPro HIC | C4 | Hydrophobic Interaction (HIC) | Non-Porous | 4 µm2.3 µm | Analytical (1 - 8 mm ID) |
