SUMICHIRAL OA
Chiral columns for enantiomer separation by HPLC.
On SUMICHIRAL OA columns, direct separation of various enantiomers can be realized effectively and efficiently. Enantiomeric separation is achieved via the various diastereomeric interactions such as hydrogen bonding, charge transfer, and host-guest interactions.
SUMICHIRAL OA columns are useful for accurate determination of optical purity and prep chromatography of pure enantiomers for biologically active compounds such as pharmaceuticals, pesticides, and perfumes.
Characteristics
- Available in Improved Pirkle Type, Ligand Exchange Type, and Host-guest Type
- High theoretical plate count equates to high resolution
- Increased chemical stability offers long column lifetime
- Enantiomeric stationary phases give inverse elution orders, resulting in accurate determination of optical purity and efficient preparative chromatography of enantiomers
Phase Comparison
This table gives an overview of the different SUMICHIRAL OA phases.
| Standard Type | Inverted Type | |||
|---|---|---|---|---|
| SUMICHIRAL | Chiral Component | SUMICHIRAL | Mode** | |
| OA-2000 | (R)-phenylglycine | OA-2000S | NP | |
| OA-2500* | (R)-1-naphthylglycine | OA-2500S | RP | |
| OA-3100 | (S)-valine | OA-3100R | NP, RP | |
| OA-3200 | (S)-tert-leucine | OA-3200R | NP, RP | |
| OA-3300* | (R)-phenylglycine | OA-3300R | NP, RP | |
| OA-4000 | (S)-valine (S)-1-(a-naphthyl)ethylamine | OA-4000R | NP | |
| OA-4100 | (S)-valine (R)-1-(a-naphthyl)ethylamine | OA-4100R | NP | |
| OA-4400 | (S)-proline (S)-1-(a-naphthyl)ethylamine | OA-4400R | NP | |
| OA-4500 | (S)-proline (R)-1-(a-naphthyl)ethylamine | OA-4500R | NP | |
| OA-4600 | (S)-tert-leucine (S)-1-(a-naphthyl)ethylamine | OA-4600R | NP | |
| OA-4700* | (S)-tert-leucine (R)-1-(a-naphthyl)ethylamine | OA-4700R | NP | |
| OA-4800 | (S)-indoline-2-carboxylic acid (S)-1-(a-naphthyl)ethylamine | ~ | NP | |
| OA-4900* | (S)-indoline-2-carboxylic acid (R)-1-(a-naphthyl)ethylamine | ~ | NP | |
| OA-5000* | (D)-penicillamine | OA-5000L | RP | |
| OA-6000 | (L)-tartaric acid (S)-1-(a-naphthyl)ethylamine | OA-6000L | RP | |
| OA-6100 | (L)-tartaric acid, (S)-valine (S)-1-(a-naphthyl)ethylamine | OA-6100L | RP | |
| OA-7000* | ß-cyclodextrin with novel spacer | ~ | RP | |
| OA-7100 | ß-cyclodextrin | ~ | RP | |
| OA-7500 | methyl- ß-cyclodextrin | ~ | RP | |
| OA-7600 | methyl- α-cyclodextrin | ~ | RP | |
| OA-7700 | acetyl- ß-cyclodextrin with novel spacer | ~ | RP | |
| OA-8000* | chiral pseudo-18-crown-6 ether | ~ | NP, RP | |
* Most popular phases
** NP: normal-phase mode; RP: reversed-phase mode
~ Enantiomeric stationary phases (inverted types) are available with the exception of OA-4800, 4900, 7000 series, and 8000. On these phases, the elution order of enantiomer is inverted.
Available Formats
- Analytical Columns & Guards (4.0 & 8.0 mm ID)
- Preparative Columns (10 & 20 mm ID)
Note: Specific availability varies by phase.
LC Columns & Accessories
| Product | Phase / Type | Separation Mode(s) | Pore Sizes | Particle Sizes | pH Range | Available Formats | Link to Order |
|---|---|---|---|---|---|---|---|
| SUMICHIRAL OA | Enantiomer Separation | Chiral | - | - | - | Analytical (1 - 8 mm ID)Preparative (10 mm ID & above) |
