CaptureSMB for the continuous purification of mAbs with high productivity and load
CaptureSMB is a twin column periodic countercurrent (PCC) process used for the continuous purification of monoclonal antibodies (mAbs) and antibody fragments using affinity resins such as Protein A and Protein L. CaptureSMB has been implemented at lab and GMP production scale with significant benefits over single-column batch chromatography
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Hybrid Approach to Continuous Downstream Biomanufacturing