Prep HPLC Columns (10 mm ID & above)
Preparative Columns for HPLC
Inner Diameter Range: 10 – 300 mm
YMC offers HPLC columns in a variety of sizes and hardware types to fill a wide range of chromatographic needs. Our standard preparative hardware range includes columns and guards with an inner diameter of 10 – 50 mm for most phases, with some available in 70 – 300 mm ID.
YMC-Actus SP spring-assisted axial compression columns as well as YMC glass columns provide additional sizes and hardware configurations. With our optional packing services, these products can also be delivered ready for use.
As always, if you have a specific need that you don’t see on our website, please contact our customer service team or your local YMC rep. Special order or custom options may be available.
Hardware Specifications
Below is an overview of the different types of prepacked preparative hardware that we offer.
Please note: not all combinations of ID and length are available and some hardware types are only available for certain products in specific particle sizes. See column selection pages or contact us for assistance.
| 10 – 30 mm ID Columns | ||
|---|---|---|
| Hardware Type | Column | Guard Column |
| Part # Ending | WT | WTG |
| Available IDs | 10, 20, 30 mm | |
| Available Lengths | 30, 50, 75, 100, 150, 250, 300 mm | 30 mm |
| Max Pressure | 100 bar | |
| Port Depth | 3.3 mm (0.13″), 1/16″ | |
| 50 – 200 mm ID Columns | ||
|---|---|---|
| Hardware Type | Flanged Column | Flanged Guard Column |
| Part # Ending | AR/DR | ARG/DRG |
| Available IDs | 50, 70, 100, 150, 200 mm | 50 mm |
| Available Lengths | 50, 100, 250, 300, 500, 1000 mm | 50 mm |
| Max Pressure | 1AR(G) / 1DR(G) – 70 bar | |
| 2AR(G) / 2DR(G) – 140 bar | ||
| Port Depth | AR(G) – 1/16″ male nut | |
| DR(G) – 1/8″ female nut | ||
YMC-Actus preparative columns were developed by applying the same technology used in Dynamic Axial Compression (DAC) columns. The column bed is compressed when attaching the inlet end assembly of the YMC-Actus hardware. This provides increased bed density (10% higher than that of conventional columns) and bed uniformity. Packed with YMC resins, Actus columns have been shown to maintain high stability under high flow rates and steep gradient conditions.
| Hardware Type | YMC-Actus Prep Column | ||
|---|---|---|---|
| Part # Ending | WX | DX | AX |
| Available IDs | 20, 30 mm | 50 mm | |
| Available Lengths | 50, 75, 100, 150, 250 mm | 50, 100, 150, 250 mm | |
| Max Pressure | 300 bar (for 5μm) | 200 bar (for 5μm) | |
| Connection | Female Swagelok nut connection (1/8”) | ||
| Fitting | 1/8″ | 1/16″ | |
Can be used with both WT and WX style columns
Part # Ending: CC(N)
Standard IDs: 10, 20, 30 mm
Standard Lengths: 10 mm
Max Pressure: 300 bar
Port Depth: 3.3 mm (0.13”), 1/16”
Holder Part #: XPCHSPW1 (10 mm ID guards)
XPGHFSP20ID (20 mm ID guards)
XPGHFSP30ID (30 mm ID guards)
(Note: holders are sold separately)
10 mm ID Guard Cartridge (CC) and Holder (XPCHSPW1)
20 / 30 mm ID Guard Cartridge (CCN) and Holder (XPGHFSP20ID / XPGHFSP30ID)
Product Availability
Preparative column dimensions are generally available for resins with 5 μm (and higher where applicable) particle sizes. View the individual product pages to find more in-depth information or place an order. Not all combinations of particle/pore size, ID/length/hardware type are available, but special order configurations may be possible. If you don’t see the specifications you need, please contact us for assistance.
| Product | Columns | Guards | ||||
|---|---|---|---|---|---|---|
| WT (Original Hardware) |
WX (Actus Hardware) |
DX/AX (Actus Hardware) |
DR/AR (Original Hardware) |
CC(N) | WTG | |
| 10 – 30 mm ID | 20 – 30 mm ID | 50 mm ID | 50 – 200 mm ID | 10 – 30 mm ID | ||
| YMC-Triart Series | 10 mm ID | X | X | X | X | |
| CHIRAL ART | 10 mm ID | X | X | X | X | |
| J’Sphere ODS Series | X | X | X | X | ||
| YMCbasic | X | X | X | X | X | X |
| YMC-Pack C4(-HG) | X | X | X | X | ||
| YMC-Pack C8(-HG) | X | X | X | X | ||
| YMC-Pack CN(-HG) | X | X | X | X | ||
| YMC-Pack Diol(-HG) | X | X | X | |||
| YMC-Pack Diol-NP(-HG) | X | X | X | X | ||
| YMC-Pack NH2 | X | X | X | |||
| YMC-Pack ODS-A(-HG) | 10 mm ID | X | X | X | X | X |
| YMC-Pack ODS-AL | X | X | X | X | X | X |
| YMC-Pack ODS-AM | X | X | X | X | X | X |
| YMC-Pack ODS-AQ(-HG) | 10 mm ID | X | X | X | X | X |
| YMC-Pack Ph(-HG) | X | X | X | X | ||
| YMC-Pack Polyamine II | X | X | X | |||
| YMC-Pack PVA-SIL | X | X | X | X | ||
| YMC-Pack SIL(-HG) | X | X | X | X | ||
| YMC-Pack TMS(-HG) | X | X | X | X | ||
| YMC-Pack Pro Series | 10 mm ID | X | X | X | X | |
Advanced Prep HPLC Columns for Efficient Separation and Purification
YMC offers a comprehensive range of preparative HPLC columns designed to deliver exceptional performance. Our prep columns provide high efficiency and reliability for diverse preparative applications, ensuring that labs can achieve precise, high-purity separations.
Key Features of Our Prep HPLC Columns
YMC’s preparative columns are engineered with flexibility in mind, allowing for use across a wide array of applications. Each column is precision-packed with YMC resin to support high flow rates and minimize back pressure, which is crucial for maintaining stability over extended runs. The advanced design of our preparative HPLC solutions ensures seamless scalability, making it easy to transition from analytical HPLC to preparative scale operations.
Versatile Preparative HPLC Column Options
Our prep columns are available in various configurations to meet specific separation needs. We offer multiple types of preparative column hardware packed with resins from YMC’s catalog of stationary phases including C18s, C8s, and other bonded phases. This variety ensures a compatible product for many preparative processes. In addition, YMC provides prep HPLC columns that are optimized for durability and reproducibility, allowing researchers to achieve consistent results across multiple particle sizes.
Precision and Reliability in Preparative Scale
YMC’s preparative scale HPLC columns are ideal for high-throughput chromatography environments. These columns offer enhanced robustness and are available with inner diameters ranging from 10 mm to 300 mm, providing effective solutions for various sample conditions and purification challenges. With our prep HPLC products, laboratories can benefit from efficient separations, reduced solvent consumption, and extended column lifetimes.
Expert Support and Services for HPLC Prep
YMC is committed to providing superior support and services for all our prep HPLC columns. Our team of experts is available to assist with troubleshooting and process optimization to ensure that you achieve the desired results. Additionally, we offer a variety of resources and technical documentation to help you maximize the performance of your preparative HPLC columns.
Order Your Prep HPLC Columns Today
Explore our catalog to find the right preparative HPLC columns for your specific applications. YMC offers an array of products that are suitable for stationary phase selection, method development, and scaling up from analytical to preparative chromatography. Place an order today to see how our prep HPLC columns can enhance your lab’s productivity. Contact us for more information or to request a quote.
